Synchronization of C. Elegans through high-throughput separation of eggs in a spiral microfluidic chip

Samuel Sofela, Sarah Sahloul, Taehong Kwon, Jongyoon Han, Majid Ebrahimi Warkiani, Yong Ak Song

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work, we report a high-throughput sorting of C. elegans embryos from a mixed-age worm population in a spiral microfluidic chip for synchronization. Using inertial forces in the spiral chip, C. elegans eggs could efficiently be focused along the inner channel wall and separated out with high sorting efficiency and purity.

Original languageEnglish (US)
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages1100-1101
Number of pages2
ISBN (Electronic)9780692941836
StatePublished - Jan 1 2020
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: Oct 22 2017Oct 26 2017

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
CountryUnited States
CitySavannah
Period10/22/1710/26/17

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Keywords

  • C. elegans
  • High-throughput sorting
  • Inertial microfluidics
  • Spiral microfluidic chip

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Sofela, S., Sahloul, S., Kwon, T., Han, J., Warkiani, M. E., & Song, Y. A. (2020). Synchronization of C. Elegans through high-throughput separation of eggs in a spiral microfluidic chip. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1100-1101). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.