@article{01441d812f174a3e932e7846615dfd9e,
title = "Synchrotron X-ray imaging via ultra-small-angle scattering: Principles of quantitative analysis and application in studying bone integration to synthetic grafting materials",
abstract = "Optimized experimental conditions for extracting accurate information at subpixel length scales from analyzer-based X-ray imaging were obtained and applied to investigate bone regeneration by means of synthetic β-TCP grafting materials in a rat calvaria model. The results showed a 30% growth in the particulate size due to bone ongrowth/ingrowth within the critical size defect over a 1-month healing period.",
keywords = "Bone, Grafting material, In vivo, Synchrotron, Ultra-small-angle scattering",
author = "Morelh{\~a}o, {S{\'e}rgio L.} and Coelho, {Paulo G.} and H{\"o}nnicke, {Marcelo G.}",
note = "Funding Information: Acknowledgments The authors gratefully acknowledge Z. Zhong for valuable discussions and Dean Connor Jr. for the expert technical assistance. Research was supported by the Brazilian agency FAPESP and CNPq. Use of the X15A beamline was supported by the U.S. Department of Energy contract no. DE-AC02-98CH10886 and by NIH grant R01 AR48292.",
year = "2010",
month = apr,
doi = "10.1007/s00249-009-0541-y",
language = "English (US)",
volume = "39",
pages = "861--865",
journal = "European Biophysics Journal",
issn = "0175-7571",
publisher = "Springer Verlag",
number = "5",
}