Synthesis of 2-Octalones from Quinaldine

Robert V. Stevens, Jimmy W. Canary

Research output: Contribution to journalArticlepeer-review


The addition of a methyl vinyl ketone unit to a cyclic ketone to form a new carbocyclic ring (the Robinson an-nulation1) has found many applications in the synthesis of organic compounds.2 Since the reaction in its original form suffers from low yields and only moderate regio-chemical control, synthetic chemists have developed various alternatives, many of which have been applied to the total synthesis of natural products.3 In this connection, heterocycles in which lie “hidden” or “masked” ketones or enols have proven especially fruitful4.

Original languageEnglish (US)
Pages (from-to)2237-2240
Number of pages4
JournalJournal of Organic Chemistry
Issue number7
StatePublished - 1990

ASJC Scopus subject areas

  • Organic Chemistry


Dive into the research topics of 'Synthesis of 2-Octalones from Quinaldine'. Together they form a unique fingerprint.

Cite this