TY - JOUR
T1 - Synthesis of artificial receptors as potential candidates for recognition and binding of pterin analogs
AU - Papadopoulou, Maria V.
AU - Goswami, Shyamaprosad
AU - Hamilton, Andrew D.
PY - 1995
Y1 - 1995
N2 - Open chain podands 2a‐c and macrocycles 2d‐e have been synthesized as potential candidates for 4‐aminopterin recognition and binding, featuring Hbonding characteristics and “stacking interaction” 2e. Preliminary binding studies between 6, 7, and 8 (simpler analogs of the above 2a‐e) as “bosts” and appropriate “guests”, showed that carbamates 2a and 2e are the most promising receptors for 4‐aminopterin binding.
AB - Open chain podands 2a‐c and macrocycles 2d‐e have been synthesized as potential candidates for 4‐aminopterin recognition and binding, featuring Hbonding characteristics and “stacking interaction” 2e. Preliminary binding studies between 6, 7, and 8 (simpler analogs of the above 2a‐e) as “bosts” and appropriate “guests”, showed that carbamates 2a and 2e are the most promising receptors for 4‐aminopterin binding.
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U2 - 10.1002/jhet.5570320250
DO - 10.1002/jhet.5570320250
M3 - Article
AN - SCOPUS:0029045987
SN - 0022-152X
VL - 32
SP - 675
EP - 681
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
IS - 2
ER -