Synthesis of high throughput ibuprofen nanoparticles via supercritical CO2 processing

Sudhir Kumar Sharma; Ramesh Jagannathan

doi:10.1109/NANO46743.2019.8993945

Synthesis of high throughput ibuprofen nanoparticles via supercritical CO₂ processing

Sudhir Kumar Sharma, Ramesh Jagannathan

General Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

High throughput ibuprofen nanoparticles with a yield up to 80 % (w/w) are synthesized via supersonic jet expansion of the supercritical CO2 processing. The effect of four different surfactants on the size of ibuprofen nanoparticles were investigated. Drop casting of these aqueous solutions on a quartz substrate and resulted in stable, viscous liquid films observed by optical, atomic force microscopy (AFM) and scanning electron microscopy (SEM). X-ray diffraction (XRD) and confocal Raman confirmed that these nanoparticles have retained their structural and chemical identity after rapid expansion of a supercritical solution (RESS) processing.

Original language	English (US)
Title of host publication	19th IEEE International Conference on Nanotechnology, NANO 2019
Publisher	IEEE Computer Society
Pages	203-206
Number of pages	4
ISBN (Electronic)	9781728128917
DOIs	https://doi.org/10.1109/NANO46743.2019.8993945
State	Published - Jul 2019
Event	19th IEEE International Conference on Nanotechnology, NANO 2019 - Macau, China Duration: Jul 22 2019 → Jul 26 2019

Publication series

Name	Proceedings of the IEEE Conference on Nanotechnology
Volume	2019-July
ISSN (Print)	1944-9399
ISSN (Electronic)	1944-9380

Conference

Conference	19th IEEE International Conference on Nanotechnology, NANO 2019
Country/Territory	China
City	Macau
Period	7/22/19 → 7/26/19

Keywords

Ibuprofen nanoparticles
RESS
Supercritical fluids

ASJC Scopus subject areas

Bioengineering
Electrical and Electronic Engineering
Materials Chemistry
Condensed Matter Physics

Access to Document

10.1109/NANO46743.2019.8993945

Cite this

Synthesis of high throughput ibuprofen nanoparticles via supercritical CO₂ processing. / Sharma, Sudhir Kumar; Jagannathan, Ramesh.
19th IEEE International Conference on Nanotechnology, NANO 2019. IEEE Computer Society, 2019. p. 203-206 8993945 (Proceedings of the IEEE Conference on Nanotechnology; Vol. 2019-July).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Sharma, SK & Jagannathan, R 2019, Synthesis of high throughput ibuprofen nanoparticles via supercritical CO₂ processing. in 19th IEEE International Conference on Nanotechnology, NANO 2019., 8993945, Proceedings of the IEEE Conference on Nanotechnology, vol. 2019-July, IEEE Computer Society, pp. 203-206, 19th IEEE International Conference on Nanotechnology, NANO 2019, Macau, China, 7/22/19. https://doi.org/10.1109/NANO46743.2019.8993945

@inproceedings{9f62dab4d99c4b7e844d7ecedd72f6ef,

title = "Synthesis of high throughput ibuprofen nanoparticles via supercritical CO2 processing",

abstract = "High throughput ibuprofen nanoparticles with a yield up to 80 % (w/w) are synthesized via supersonic jet expansion of the supercritical CO2 processing. The effect of four different surfactants on the size of ibuprofen nanoparticles were investigated. Drop casting of these aqueous solutions on a quartz substrate and resulted in stable, viscous liquid films observed by optical, atomic force microscopy (AFM) and scanning electron microscopy (SEM). X-ray diffraction (XRD) and confocal Raman confirmed that these nanoparticles have retained their structural and chemical identity after rapid expansion of a supercritical solution (RESS) processing.",

keywords = "Ibuprofen nanoparticles, RESS, Supercritical fluids",

author = "Sharma, {Sudhir Kumar} and Ramesh Jagannathan",

note = "Publisher Copyright: {\textcopyright} 2019 IEEE.; 19th IEEE International Conference on Nanotechnology, NANO 2019 ; Conference date: 22-07-2019 Through 26-07-2019",

year = "2019",

month = jul,

doi = "10.1109/NANO46743.2019.8993945",

language = "English (US)",

series = "Proceedings of the IEEE Conference on Nanotechnology",

publisher = "IEEE Computer Society",

pages = "203--206",

booktitle = "19th IEEE International Conference on Nanotechnology, NANO 2019",

}

TY - GEN

T1 - Synthesis of high throughput ibuprofen nanoparticles via supercritical CO2 processing

AU - Sharma, Sudhir Kumar

AU - Jagannathan, Ramesh

PY - 2019/7

Y1 - 2019/7

N2 - High throughput ibuprofen nanoparticles with a yield up to 80 % (w/w) are synthesized via supersonic jet expansion of the supercritical CO2 processing. The effect of four different surfactants on the size of ibuprofen nanoparticles were investigated. Drop casting of these aqueous solutions on a quartz substrate and resulted in stable, viscous liquid films observed by optical, atomic force microscopy (AFM) and scanning electron microscopy (SEM). X-ray diffraction (XRD) and confocal Raman confirmed that these nanoparticles have retained their structural and chemical identity after rapid expansion of a supercritical solution (RESS) processing.

AB - High throughput ibuprofen nanoparticles with a yield up to 80 % (w/w) are synthesized via supersonic jet expansion of the supercritical CO2 processing. The effect of four different surfactants on the size of ibuprofen nanoparticles were investigated. Drop casting of these aqueous solutions on a quartz substrate and resulted in stable, viscous liquid films observed by optical, atomic force microscopy (AFM) and scanning electron microscopy (SEM). X-ray diffraction (XRD) and confocal Raman confirmed that these nanoparticles have retained their structural and chemical identity after rapid expansion of a supercritical solution (RESS) processing.

KW - Ibuprofen nanoparticles

KW - RESS

KW - Supercritical fluids

UR - http://www.scopus.com/inward/record.url?scp=85081059589&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85081059589&partnerID=8YFLogxK

U2 - 10.1109/NANO46743.2019.8993945

DO - 10.1109/NANO46743.2019.8993945

M3 - Conference contribution

AN - SCOPUS:85081059589

T3 - Proceedings of the IEEE Conference on Nanotechnology

SP - 203

EP - 206

BT - 19th IEEE International Conference on Nanotechnology, NANO 2019

PB - IEEE Computer Society

T2 - 19th IEEE International Conference on Nanotechnology, NANO 2019

Y2 - 22 July 2019 through 26 July 2019

ER -