Synthetic cervical mucus formulation

Bríd T. Burruano, Roger L. Schnaare, Daniel Malamud

Research output: Contribution to journalArticle

Abstract

A synthetic formulation has been developed with viscosity, spinnbarkeit, and pH comparable to that reported for human cervical mucus. The formulation contains guar gum crosslinked with borate ion, mucin (dried porcine gastric), and a mixed preservative system in pH 7.4, 0.1M phosphate buffer. The guar gum source, mucin concentration, and method of preparation were shown to be critical factors in the performance of the formulation.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalContraception
Volume66
Issue number2
DOIs
StatePublished - Aug 2002

Keywords

  • Cervical
  • Formulation
  • Guar gum
  • Mucus

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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