Synthetic cervical mucus formulation

Bríd T. Burruano, Roger L. Schnaare, Daniel Malamud

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A synthetic formulation has been developed with viscosity, spinnbarkeit, and pH comparable to that reported for human cervical mucus. The formulation contains guar gum crosslinked with borate ion, mucin (dried porcine gastric), and a mixed preservative system in pH 7.4, 0.1M phosphate buffer. The guar gum source, mucin concentration, and method of preparation were shown to be critical factors in the performance of the formulation.

    Original languageEnglish (US)
    Pages (from-to)137-140
    Number of pages4
    JournalContraception
    Volume66
    Issue number2
    DOIs
    StatePublished - Aug 2002

    Keywords

    • Cervical
    • Formulation
    • Guar gum
    • Mucus

    ASJC Scopus subject areas

    • Reproductive Medicine
    • Obstetrics and Gynecology

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