Taking single virus detection and sizing to the limit with molecular sensitivity: The birth of nanoplasmonic-microcavity hybrid sensors

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The BioPhotonics community is buzzing at the prospect that ulta-small bio-nanoparticles such as Polio virus and protein can be detected label-free in their native state and sized one at a time. As the awareness that the claim of label-free single protein sensing through the frequency shift of a bare microcavity by A.M. Armani et al in Science in 2007 fades from lack of independent experimental confirmation or a viable physical mechanism to account for the magnitude of the reported wavelength shifts, a new approach has captured the community's interest. It is a product of a marriage between nano-optics and micro-photonics, and is poised to take label-free sensing to the limit.

Original languageEnglish (US)
Title of host publicationFrontiers in Biological Detection
Subtitle of host publicationFrom Nanosensors to Systems V
DOIs
StatePublished - 2013
EventFrontiers in Biological Detection: From Nanosensors to Systems V - San Francisco, CA, United States
Duration: Feb 2 2013Feb 3 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8570
ISSN (Print)1605-7422

Other

OtherFrontiers in Biological Detection: From Nanosensors to Systems V
CountryUnited States
CitySan Francisco, CA
Period2/2/132/3/13

Keywords

  • biosensing
  • microcavity
  • plasmonic enhancement
  • plasmonic epitope
  • whispering-gallery-mode

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Arnold, S. (2013). Taking single virus detection and sizing to the limit with molecular sensitivity: The birth of nanoplasmonic-microcavity hybrid sensors. In Frontiers in Biological Detection: From Nanosensors to Systems V [85700D] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8570). https://doi.org/10.1117/12.2003106