Abstract
Finding a method for label-free sensing of individual protein is considered the "Holy Grail" in the bio-sensing field. An ideal technology that could do this would be able to follow the sensing of biological antigen-antibody interactions in their native form and in real-time without interfering tags. The challenge is great, however the rewards are likely greater. To date the most sensitive photonic label-free transducer is a resonant biosensor in the form of a Ring Resonator or Whispering Gallery Mode (WGM) resonator for which there have been a number of recent reviews [1, 2].
| Original language | English (US) |
|---|---|
| Title of host publication | Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale |
| Subtitle of host publication | Plamonics, Photonic Materials and Sub-Wavelength Resolution |
| Editors | Baldassare Di Bartolo, Luciano Silvestri, John Collins |
| Pages | 271-285 |
| Number of pages | 15 |
| DOIs | |
| State | Published - 2013 |
Publication series
| Name | NATO Science for Peace and Security Series B: Physics and Biophysics |
|---|---|
| ISSN (Print) | 1874-6500 |
ASJC Scopus subject areas
- Biotechnology
- Biophysics
- Physics and Astronomy(all)
- Electrical and Electronic Engineering
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Cite this
Arnold, S., Dantham, V. R., Rivilis, N., & Holler, S. (2013). Taking whispering gallery mode biosensing to the single protein limit. In B. Di Bartolo, L. Silvestri, & J. Collins (Eds.), Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale: Plamonics, Photonic Materials and Sub-Wavelength Resolution (pp. 271-285). (NATO Science for Peace and Security Series B: Physics and Biophysics). https://doi.org/10.1007/978-94-007-5313-6-12