Taking whispering gallery mode biosensing to the single protein limit

Steve Arnold, V. R. Dantham, N. Rivilis, S. Holler

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Finding a method for label-free sensing of individual protein is considered the "Holy Grail" in the bio-sensing field. An ideal technology that could do this would be able to follow the sensing of biological antigen-antibody interactions in their native form and in real-time without interfering tags. The challenge is great, however the rewards are likely greater. To date the most sensitive photonic label-free transducer is a resonant biosensor in the form of a Ring Resonator or Whispering Gallery Mode (WGM) resonator for which there have been a number of recent reviews [1, 2].

Original languageEnglish (US)
Title of host publicationNano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale
Subtitle of host publicationPlamonics, Photonic Materials and Sub-Wavelength Resolution
PublisherSpringer Verlag
Number of pages15
ISBN (Print)9789400753129
StatePublished - 2013

Publication series

NameNATO Science for Peace and Security Series B: Physics and Biophysics
ISSN (Print)1874-6500

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • General Physics and Astronomy
  • Electrical and Electronic Engineering


Dive into the research topics of 'Taking whispering gallery mode biosensing to the single protein limit'. Together they form a unique fingerprint.

Cite this