Taking whispering gallery mode biosensing to the single protein limit

Steve Arnold; V. R. Dantham; N. Rivilis; S. Holler

doi:10.1007/978-94-007-5313-6_12

Taking whispering gallery mode biosensing to the single protein limit

Steve Arnold, V. R. Dantham, N. Rivilis, S. Holler

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Finding a method for label-free sensing of individual protein is considered the "Holy Grail" in the bio-sensing field. An ideal technology that could do this would be able to follow the sensing of biological antigen-antibody interactions in their native form and in real-time without interfering tags. The challenge is great, however the rewards are likely greater. To date the most sensitive photonic label-free transducer is a resonant biosensor in the form of a Ring Resonator or Whispering Gallery Mode (WGM) resonator for which there have been a number of recent reviews [1, 2].

Original language	English (US)
Title of host publication	Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale
Subtitle of host publication	Plamonics, Photonic Materials and Sub-Wavelength Resolution
Publisher	Springer Verlag
Pages	271-285
Number of pages	15
ISBN (Print)	9789400753129
DOIs	https://doi.org/10.1007/978-94-007-5313-6_12
State	Published - 2013

Publication series

Name	NATO Science for Peace and Security Series B: Physics and Biophysics
ISSN (Print)	1874-6500

ASJC Scopus subject areas

Biotechnology
Biophysics
Physics and Astronomy(all)
Electrical and Electronic Engineering

Access to Document

10.1007/978-94-007-5313-6_12

Cite this

Arnold, S., Dantham, V. R., Rivilis, N., & Holler, S. (2013). Taking whispering gallery mode biosensing to the single protein limit. In Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale: Plamonics, Photonic Materials and Sub-Wavelength Resolution (pp. 271-285). (NATO Science for Peace and Security Series B: Physics and Biophysics). Springer Verlag. https://doi.org/10.1007/978-94-007-5313-6_12

Taking whispering gallery mode biosensing to the single protein limit. / Arnold, Steve; Dantham, V. R.; Rivilis, N. et al.

Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale: Plamonics, Photonic Materials and Sub-Wavelength Resolution. Springer Verlag, 2013. p. 271-285 (NATO Science for Peace and Security Series B: Physics and Biophysics).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Arnold, S, Dantham, VR, Rivilis, N & Holler, S 2013, Taking whispering gallery mode biosensing to the single protein limit. in Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale: Plamonics, Photonic Materials and Sub-Wavelength Resolution. NATO Science for Peace and Security Series B: Physics and Biophysics, Springer Verlag, pp. 271-285. https://doi.org/10.1007/978-94-007-5313-6_12

Arnold S, Dantham VR, Rivilis N, Holler S. Taking whispering gallery mode biosensing to the single protein limit. In Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale: Plamonics, Photonic Materials and Sub-Wavelength Resolution. Springer Verlag. 2013. p. 271-285. (NATO Science for Peace and Security Series B: Physics and Biophysics). doi: 10.1007/978-94-007-5313-6_12

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Taking whispering gallery mode biosensing to the single protein limit

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