Technical advances in proton transfer reaction-mass spectrometry and new fields of application

Philipp Sulzer, Alfons Jordan, Lukas Märk, Christopher A. Mayhew, Kurt Becker, Tilmann D. Märk

Research output: Contribution to journalArticle

Abstract

Technical advances in proton transfer reaction-mass spectrometry (PTR-MS) and new fields of application are discussed. One recent development in PTR-MS is the introduction of time-of-flight (TOF) mass analyzers. Studies have found that the PTR-TOF 8000 achieves a mass resolution up to 8000, allowing most isobaric VOCs to be distinguished easily. A major development in primary ion preparation is the use of switchable reagent ions (SRI), in which the primary ions can be switched from H3O+ to O2+ and NO+ within seconds. Food and flavor scientists benefit from the technique's real-time quantification with very short response times, which allows for nosespace analysis during eating or drinking. Although several military institutions own and deploy PTR-MS instruments for the detection and analysis of illicit substances such as chemical warfare agents, the field is yet to be explored.

Original languageEnglish (US)
Pages (from-to)13-15
Number of pages3
JournalAmerican Laboratory
Volume43
Issue number9
StatePublished - Sep 2011

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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    Sulzer, P., Jordan, A., Märk, L., Mayhew, C. A., Becker, K., & Märk, T. D. (2011). Technical advances in proton transfer reaction-mass spectrometry and new fields of application. American Laboratory, 43(9), 13-15.