Techniques for and challenges in reconstructing 3D genome structures from 2D chromosome conformation capture data

Keyphrases

• Contact Data 100%
• Chromosome Conformation Capture 100%
• 3D Genome Organization 100%
• Capture Data 100%
• Chromatin 50%
• Computational Methods 50%
• Epigenetic Regulation 50%
• Brownian Dynamics 50%
• Monte Carlo Sampling 50%
• Genomic Regions 50%
• Frequency Information 50%
• Capture Technology 50%
• Genome Folding 50%
• Reconstruction Method 50%
• Biological Insight 50%
• Resolution Approach 50%
• 3D Organization 50%
• 3D Chromatin Structure 50%

Biochemistry, Genetics and Molecular Biology

• Genomic Structure 100%
• Chromosome Conformation Capture 100%
• Dynamics 50%
• Reconstruction 50%