Temporal summation and refractoriness in hypothalamic reward neurons as measured by self-stimulation behavior

Nicole Schupf Smith, Edgar E. Coons

Research output: Contribution to journalArticle

Abstract

A neurophysiological technique of double-pulse stimulation has been applied to freely moving rats with chronic indwelling electrodes in the hypothalamic reward area. Self-stimulation thresholds, measured as a function of the interpulse interval, generated curves with time constants characteristic of refractory periods and temporal synoptic summation. The results indicate a way of studying central neuronal processes for which the overt behavior of the animal is the dependent variable.

Original languageEnglish (US)
Pages (from-to)782-785
Number of pages4
JournalScience
Volume169
Issue number3947
DOIs
StatePublished - 1970

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Temporal summation and refractoriness in hypothalamic reward neurons as measured by self-stimulation behavior'. Together they form a unique fingerprint.

Cite this