Tetracycline and its analogues: A therapeutic paradigm in periodontal diseases

Mea A. Weinberg, Michael Bral

Research output: Contribution to journalReview articlepeer-review


This article discusses the use of tetracyclines in the clinical management of periodontal infections. A review of the drugs' pharmacology, pharmacokinetics, and potential adverse effects shows that they are relatively safe if used in appropriate dosages and under controlled conditions. Current data suggest that the routine use of tetracyclines in conjunction with the treatment of periodontitis is unnecessary. However, their distinctive characteristics can be utilized in different delivery systems as an adjunctive aid to conventional treatment of juvenile and refractory forms of periodontitis.

Original languageEnglish (US)
Pages (from-to)322-332
Number of pages11
JournalCritical Reviews in Oral Biology and Medicine
Issue number3
StatePublished - 1998


  • Drug therapy
  • Periodontal diseases
  • Tetracyclines
  • Therapeutic uses

ASJC Scopus subject areas

  • Otorhinolaryngology
  • General Dentistry


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