TY - BOOK
T1 - The Chemical Biology of DNA Damage
AU - Geacintov, Nicholas E.
AU - Broyde, Suse
PY - 2010/10/11
Y1 - 2010/10/11
N2 - Bringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response. Clearly divided into two main sections, Part 1 focuses on selected examples of important DNA lesions and their biological impact, while the second part covers current advances in assessing and predicting the genotoxic effects of chemicals, taking into account the biological responses mediated by the DNA repair, replication and transcription machineries. A ready reference for biochemists, toxicologists, molecular and cell biologists, and geneticists seeking a better understanding of the impact of chemicals on human health.
AB - Bringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response. Clearly divided into two main sections, Part 1 focuses on selected examples of important DNA lesions and their biological impact, while the second part covers current advances in assessing and predicting the genotoxic effects of chemicals, taking into account the biological responses mediated by the DNA repair, replication and transcription machineries. A ready reference for biochemists, toxicologists, molecular and cell biologists, and geneticists seeking a better understanding of the impact of chemicals on human health.
UR - http://www.scopus.com/inward/record.url?scp=77957580394&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957580394&partnerID=8YFLogxK
U2 - 10.1002/9783527630110
DO - 10.1002/9783527630110
M3 - Book
AN - SCOPUS:77957580394
SN - 9783527322954
BT - The Chemical Biology of DNA Damage
PB - Wiley-VCH
ER -