The comparative genomics and complex population history of Papio baboons

Jeffrey Rogers, Muthuswamy Raveendran, R. Alan Harris, Thomas Mailund, Kalle Leppälä, Georgios Athanasiadis, Mikkel Heide Schierup, Jade Cheng, Kasper Munch, Jerilyn A. Walker, Miriam K. Konkel, Vallmer E. Jordan, Cody J. Steely, Thomas O. Beckstrom, Christina Bergey, Andrew Burrell, Dominik Schrempf, Angela Noll, Maximillian Kothe, Gisela H. KoppYue Liu, Shwetha Murali, Konstantinos Billis, Fergal J. Martin, Matthieu Muffato, Laura A. Cox, James Else, Todd Disotell, Donna M. Muzny, Jane Phillips-Conroy, Bronwen Aken, Evan E. Eichler, Tomas Marques-Bonet, Carolin Kosiol, Mark A. Batzer, Matthew W. Hahn, Jenny Tung, Dietmar Zinner, Christian Roos, Clifford J. Jolly, Richard A. Gibbs, Kim C. Worley, Nicoletta Archidiacono, Oronzo Capozzi, Claudia R. Catacchio, Huyen H. Dinh, Harsha Vardhan Doddapaneni, Yi Han, John Huddleston, Shalini N. Jhangiani, Anis Karimpour-Fard, Viktoriya Korchina, Christie L. Kovar, Lukas Kuderna, Sandra L. Lee, Xiaoming Liu, Alessia Marra-Campanale, Christopher E. Mason, Marc de Manuel Montero, Kymberleigh A. Pagel, Antonio Palazzo, Jera Pecotte, Vikas Pejaver, Lenore Pipes, Veronica Searles Quick, Predrag Radivojac, Archana Raja, Brian J. Raney, Karen Rice, Mariano Rocchi, James M. Sikela, Roscoe Stanyon, Gregg W.C. Thomas, Mario Ventura, Tauras P. Vilgalys, Tomas Vinar, Lutz Walter

    Research output: Contribution to journalArticle

    Abstract

    Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus Papio) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon (Papio anubis) and whole-genome sequence data for all six extant species. We document multiple episodes of admixture and introgression during the radiation of Papio baboons, thus demonstrating their value as a model of complex evolutionary divergence, hybridization, and reticulation. These results help inform our understanding of similar cases, including modern humans, Neanderthals, Denisovans, and other ancient hominins.

    Original languageEnglish (US)
    Article numbereaau6947
    JournalScience Advances
    Volume5
    Issue number1
    DOIs
    StatePublished - Jan 30 2019

    ASJC Scopus subject areas

    • General

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  • Cite this

    Rogers, J., Raveendran, M., Harris, R. A., Mailund, T., Leppälä, K., Athanasiadis, G., Schierup, M. H., Cheng, J., Munch, K., Walker, J. A., Konkel, M. K., Jordan, V. E., Steely, C. J., Beckstrom, T. O., Bergey, C., Burrell, A., Schrempf, D., Noll, A., Kothe, M., ... Walter, L. (2019). The comparative genomics and complex population history of Papio baboons. Science Advances, 5(1), [eaau6947]. https://doi.org/10.1126/sciadv.aau6947