TY - JOUR
T1 - The effect of almonds consumption on blood pressure
T2 - A systematic review and dose-response meta-analysis of randomized control trials
AU - Li, Zhe
AU - Bhagavathula, Akshaya Srikanth
AU - Batavia, Mitchell
AU - Clark, Cain
AU - Abdulazeem, Hebatullah M.
AU - Rahmani, Jamal
AU - Yin, Fuyu
N1 - Publisher Copyright:
© 2020 The Author(s)
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Almond is rich in antioxidants and phytochemicals such as methylquercetin, protocatechuic acid, catechin, flavonoids, p-hydroxybenzoic acid, resveratrol, vanillic acid, and kaempferol. The aim of the present study was to systematically review and dose-response meta-analyses the effects of almond consumption on systolic and diastolic blood pressure (SBP/DBP), respectively, in Randomized Controlled Trials (RCTs). A systematic search was performed in PubMed/MEDLINE, web of sciences and SCOPUS by 2 researchers, independently to identify randomised controlled trials up to July 2019. There were no time or language restrictions. PRISMA guidelines were followed in conducting this meta-analysis. Fifteen studies with 21 arms, containing 853 participants, reported SBP as an outcome measure. Pooled results showed significant reduction in SBP (WMD: −0.90 mmHg, 95% CI: −1.74, −0.06, Pheterogeneity = 0.94) by almond intervention. There is no significant effect from almond consumption on DBP (WMD: 0.67 mmHg, 95% CI: −1.93, 0.60, Pheterogeneity = 0.001). Meta-regression analysis showed dose of used almond (g/d) as source of heterogeneity between results of DBP. In conclusion results of this meta-analysis showed reduce effect of Almonds on systolic blood pressure.
AB - Almond is rich in antioxidants and phytochemicals such as methylquercetin, protocatechuic acid, catechin, flavonoids, p-hydroxybenzoic acid, resveratrol, vanillic acid, and kaempferol. The aim of the present study was to systematically review and dose-response meta-analyses the effects of almond consumption on systolic and diastolic blood pressure (SBP/DBP), respectively, in Randomized Controlled Trials (RCTs). A systematic search was performed in PubMed/MEDLINE, web of sciences and SCOPUS by 2 researchers, independently to identify randomised controlled trials up to July 2019. There were no time or language restrictions. PRISMA guidelines were followed in conducting this meta-analysis. Fifteen studies with 21 arms, containing 853 participants, reported SBP as an outcome measure. Pooled results showed significant reduction in SBP (WMD: −0.90 mmHg, 95% CI: −1.74, −0.06, Pheterogeneity = 0.94) by almond intervention. There is no significant effect from almond consumption on DBP (WMD: 0.67 mmHg, 95% CI: −1.93, 0.60, Pheterogeneity = 0.001). Meta-regression analysis showed dose of used almond (g/d) as source of heterogeneity between results of DBP. In conclusion results of this meta-analysis showed reduce effect of Almonds on systolic blood pressure.
KW - Almond
KW - Diastolic blood pressure
KW - Meta-analysis
KW - Systolic blood pressure
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U2 - 10.1016/j.jksus.2020.01.013
DO - 10.1016/j.jksus.2020.01.013
M3 - Review article
AN - SCOPUS:85078542009
SN - 1018-3647
VL - 32
SP - 1757
EP - 1763
JO - Journal of King Saud University - Science
JF - Journal of King Saud University - Science
IS - 2
ER -