The effect of cyclic AMP on morphogenesis and enzyme accumulation in Dictyostelium discoideum

Marion Nestle; Maurice Sussman

doi:10.1016/0012-1606(72)90002-4

The effect of cyclic AMP on morphogenesis and enzyme accumulation in Dictyostelium discoideum

Marion Nestle, Maurice Sussman

Nutrition and Food Studies

Research output: Contribution to journal › Article › peer-review

Abstract

When 3′,5′-cyclic AMP is applied externally to migrating slugs and to cell aggregates during particular stages of morphogenesis, it disturbs the normal polarity and dominance relationships among the cells in a specific manner. It also interferes with the developmental programs of at least two enzymes that are needed for fruit construction.

Original language	English (US)
Pages (from-to)	545-554
Number of pages	10
Journal	Developmental Biology
Volume	28
Issue number	4
DOIs	https://doi.org/10.1016/0012-1606(72)90002-4
State	Published - Aug 1972

ASJC Scopus subject areas

Molecular Biology
Developmental Biology
Cell Biology

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10.1016/0012-1606(72)90002-4

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title = "The effect of cyclic AMP on morphogenesis and enzyme accumulation in Dictyostelium discoideum",

abstract = "When 3′,5′-cyclic AMP is applied externally to migrating slugs and to cell aggregates during particular stages of morphogenesis, it disturbs the normal polarity and dominance relationships among the cells in a specific manner. It also interferes with the developmental programs of at least two enzymes that are needed for fruit construction.",

author = "Marion Nestle and Maurice Sussman",

note = "Funding Information: This work was supported by Grant GB5976X from the National Science Foundation. Funding Information: M. N. was a postdoctoral trainee, Graduate Training Program in Developmental Biology (National Institutes of Health Tl HD-22). M. S. was the recipient of a Career Development Award from the National Institutes of Health (K3-GM-1313).",

year = "1972",

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AU - Sussman, Maurice

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The effect of cyclic AMP on morphogenesis and enzyme accumulation in Dictyostelium discoideum

Abstract

ASJC Scopus subject areas

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