The evolution of molecular genetic pathways and networks

Jennifer M. Cork, Michael D. Purugganan

Research output: Contribution to journalReview article

Abstract

There is growing interest in the evolutionary dynamics of molecular genetic pathways and networks, and the extent to which the molecular evolution of a gene depends on its position within a pathway or network, as well as over-all network topology. Investigations on the relationships between network organization, topological architecture and evolutionary dynamics provide intriguing hints as to how networks evolve. Recent studies also suggest that genetic pathway and network structures may influence the action of evolutionary forces, and may play a role in maintaining phenotypic robustness in organisms.

Original languageEnglish (US)
Pages (from-to)479-484
Number of pages6
JournalBioEssays
Volume26
Issue number5
DOIs
StatePublished - May 2004

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'The evolution of molecular genetic pathways and networks'. Together they form a unique fingerprint.

  • Cite this