TY - GEN
T1 - The FitzHugh-Nagumo model
T2 - 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
AU - Faghih, Rose T.
AU - Savla, Ketan
AU - Dahleh, Munther A.
AU - Brown, Emery N.
PY - 2010
Y1 - 2010
N2 - In this paper, we revisit the issue of the utility of the FitzHugh-Nagumo (FHN) model for capturing neuron firing behaviors. It has been noted (e.g., see [6]) that the FHN model cannot exhibit certain interesting firing behaviors such as bursting. We illustrate that, by allowing time-varying parameters for the FHN model, one could overcome such limitations while still retaining the low order complexity of the FHN model. We also highlight the utility of the FHN model from an estimation perspective by presenting a novel parameter estimation method that exploits the multiple time scale feature of the FHN model, and compare the performance of this method with the Extended Kalman Filter through illustrative examples.
AB - In this paper, we revisit the issue of the utility of the FitzHugh-Nagumo (FHN) model for capturing neuron firing behaviors. It has been noted (e.g., see [6]) that the FHN model cannot exhibit certain interesting firing behaviors such as bursting. We illustrate that, by allowing time-varying parameters for the FHN model, one could overcome such limitations while still retaining the low order complexity of the FHN model. We also highlight the utility of the FHN model from an estimation perspective by presenting a novel parameter estimation method that exploits the multiple time scale feature of the FHN model, and compare the performance of this method with the Extended Kalman Filter through illustrative examples.
UR - http://www.scopus.com/inward/record.url?scp=78650802551&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650802551&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2010.5627326
DO - 10.1109/IEMBS.2010.5627326
M3 - Conference contribution
C2 - 21096631
AN - SCOPUS:78650802551
SN - 9781424441235
T3 - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
SP - 4116
EP - 4119
BT - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Y2 - 31 August 2010 through 4 September 2010
ER -