The function of Dmrt genes in vertebrate development: It is not just about sex

Chang Soo Hong, Byung Yong Park, Jean Pierre Saint-Jeannet

Research output: Contribution to journalReview article

Abstract

The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalDevelopmental Biology
Volume310
Issue number1
DOIs
StatePublished - Oct 1 2007

Keywords

  • DM domain
  • Dmrt
  • Gonads
  • Laterality
  • Nasal placode
  • Olfactory system
  • Sex determination
  • Somites

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

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