Abstract
A new concept and device for forming a stationary gradient with flow, yet without shear, is presented. A microfluidic probe (MFP) with four apertures is immersed in a fluid and placed atop a substrate. Pairwise injection and aspiration creates a stagnant point at the center of the probe where a chemical gradient can be formed. The gradient can be shaped by adjusting the flow rate and moved across the surface with the MFP. A prototype and proof of concept simulations and experiments are presented.
Original language | English (US) |
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Pages | 841-843 |
Number of pages | 3 |
State | Published - 2008 |
Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: Oct 12 2008 → Oct 16 2008 |
Other
Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
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Country/Territory | United States |
City | San Diego, CA |
Period | 10/12/08 → 10/16/08 |
Keywords
- Gradient
- Microfluidic probe
- Stagnant point
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering