The generation of stationary chemical gradients around stagnant points using a microfluidic probe

Mohammad A. Qasaimeh, Poulomi Sanyal, Roozbeh Safavieh, Cecile M. Perrault, Arthur Queval, David Juncker

Research output: Contribution to conferencePaperpeer-review

Abstract

A new concept and device for forming a stationary gradient with flow, yet without shear, is presented. A microfluidic probe (MFP) with four apertures is immersed in a fluid and placed atop a substrate. Pairwise injection and aspiration creates a stagnant point at the center of the probe where a chemical gradient can be formed. The gradient can be shaped by adjusting the flow rate and moved across the surface with the MFP. A prototype and proof of concept simulations and experiments are presented.

Original languageEnglish (US)
Pages841-843
Number of pages3
StatePublished - 2008
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/TerritoryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

Keywords

  • Gradient
  • Microfluidic probe
  • Stagnant point

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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