The guanidinium group in molecular recognition: Design and synthetic approaches

Brendan P. Orner; Andrew D. Hamilton

doi:10.1023/A:1014433715641

The guanidinium group in molecular recognition: Design and synthetic approaches

Brendan P. Orner, Andrew D. Hamilton

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Department of Chemistry, PO Box 208107, Yale University, New Haven CT, USA The guanidinium group is found in many natural products and has been extensively incorporated into various drug designs as well as artificial receptor structures. In this paper we critically review the various synthetic routes to guanidiniums and describe a novel approach that allows the mild formation of multi-substituted derivatives.

Original language	English (US)
Pages (from-to)	141-147
Number of pages	7
Journal	Journal of Inclusion Phenomena
Volume	41
Issue number	1-4
DOIs	https://doi.org/10.1023/A:1014433715641
State	Published - Dec 2001

Keywords

Guanidinium

ASJC Scopus subject areas

Food Science
Chemistry(all)
Condensed Matter Physics

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10.1023/A:1014433715641

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abstract = "Department of Chemistry, PO Box 208107, Yale University, New Haven CT, USA The guanidinium group is found in many natural products and has been extensively incorporated into various drug designs as well as artificial receptor structures. In this paper we critically review the various synthetic routes to guanidiniums and describe a novel approach that allows the mild formation of multi-substituted derivatives.",

keywords = "Guanidinium",

author = "Orner, {Brendan P.} and Hamilton, {Andrew D.}",

note = "Funding Information: We thank Drs. Andrew J. Carr and Brian R. Linton for helpful discussions and the National Science Foundation for financial support of this work. Copyright: Copyright 2005 Elsevier B.V., All rights reserved.",

year = "2001",

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doi = "10.1023/A:1014433715641",

language = "English (US)",

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AU - Hamilton, Andrew D.

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PY - 2001/12

Y1 - 2001/12

N2 - Department of Chemistry, PO Box 208107, Yale University, New Haven CT, USA The guanidinium group is found in many natural products and has been extensively incorporated into various drug designs as well as artificial receptor structures. In this paper we critically review the various synthetic routes to guanidiniums and describe a novel approach that allows the mild formation of multi-substituted derivatives.

AB - Department of Chemistry, PO Box 208107, Yale University, New Haven CT, USA The guanidinium group is found in many natural products and has been extensively incorporated into various drug designs as well as artificial receptor structures. In this paper we critically review the various synthetic routes to guanidiniums and describe a novel approach that allows the mild formation of multi-substituted derivatives.

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The guanidinium group in molecular recognition: Design and synthetic approaches

Abstract

Keywords

ASJC Scopus subject areas

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