TY - JOUR
T1 - The guanidinium group in molecular recognition
T2 - Design and synthetic approaches
AU - Orner, Brendan P.
AU - Hamilton, Andrew D.
N1 - Funding Information:
We thank Drs. Andrew J. Carr and Brian R. Linton for helpful discussions and the National Science Foundation for financial support of this work.
Copyright:
Copyright 2005 Elsevier B.V., All rights reserved.
PY - 2001/12
Y1 - 2001/12
N2 - Department of Chemistry, PO Box 208107, Yale University, New Haven CT, USA The guanidinium group is found in many natural products and has been extensively incorporated into various drug designs as well as artificial receptor structures. In this paper we critically review the various synthetic routes to guanidiniums and describe a novel approach that allows the mild formation of multi-substituted derivatives.
AB - Department of Chemistry, PO Box 208107, Yale University, New Haven CT, USA The guanidinium group is found in many natural products and has been extensively incorporated into various drug designs as well as artificial receptor structures. In this paper we critically review the various synthetic routes to guanidiniums and describe a novel approach that allows the mild formation of multi-substituted derivatives.
KW - Guanidinium
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U2 - 10.1023/A:1014433715641
DO - 10.1023/A:1014433715641
M3 - Article
AN - SCOPUS:0035605659
SN - 0923-0750
VL - 41
SP - 141
EP - 147
JO - Journal of Inclusion Phenomena
JF - Journal of Inclusion Phenomena
IS - 1-4
ER -