The human mycobiome in health and disease

Lijia Cui, Alison Morris, Elodie Ghedin

Research output: Contribution to journalReview articlepeer-review

Abstract

The mycobiome, referring primarily to the fungal biota in an environment, is an important component of the human microbiome. Despite its importance, it has remained understudied. New culture-independent approaches to determine microbial diversity, such as next-generation sequencing methods, are greatly broadening our view of fungal importance. An integrative analysis of current studies shows that different body sites harbor specific fungal populations, and that diverse mycobiome patterns are associated with various diseases. By interfacing with other biomes, as well as with the host, the mycobiome probably contributes to the progression of fungus-associated diseases and plays an important role in health and disease.

Original languageEnglish (US)
Article number63
JournalGenome Medicine
Volume5
Issue number7
DOIs
StatePublished - Jul 30 2013

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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