The incredible shrinking world of DNA microarrays

Sarah J. Wheelan, Francisco Martínez Murillo, Jef D. Boeke

    Research output: Contribution to journalReview article

    Abstract

    The efficacy of microarrays in examining gene expression, gene and genome structure, protein-DNA interactions, whole-genome similarities and differences, microRNA expression, methylation (and more) is no longer in question. It is a fast-developing, cutting edge technology that has grown up along with massive sequence databases and is likely to become part of everyday patient care. Many advances have recently expanded the power and utility of microarrays; among them is our development of a new array tiling technique that dramatically increases the scope of coverage of an oligonucleotide tiling array without substantially increasing its cost.

    Original languageEnglish (US)
    Pages (from-to)726-732
    Number of pages7
    JournalMolecular BioSystems
    Volume4
    Issue number7
    DOIs
    StatePublished - 2008

    ASJC Scopus subject areas

    • Biotechnology
    • Molecular Biology

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  • Cite this

    Wheelan, S. J., Martínez Murillo, F., & Boeke, J. D. (2008). The incredible shrinking world of DNA microarrays. Molecular BioSystems, 4(7), 726-732. https://doi.org/10.1039/b706237k