The involvement of audio-motor coupling in the music-supported therapy applied to stroke patients

Antoni Rodriguez-Fornells, Nuria Rojo, Julià L. Amengual, Pablo Ripollés, Eckart Altenmüller, Thomas F. Münte

Research output: Contribution to journalArticlepeer-review


Music-supported therapy (MST) has been developed recently to improve the use of the affected upper extremity after stroke. MST uses musical instruments, an electronic piano and an electronic drum set emitting piano sounds, to retrain fine and gross movements of the paretic upper extremity. In this paper, we first describe the rationale underlying MST, and we review the previous studies conducted on acute and chronic stroke patients using this new neurorehabilitation approach. Second, we address the neural mechanisms involved in the motor movement improvements observed in acute and chronic stroke patients. Third, we provide some recent studies on the involvement of auditory-motor coupling in the MST in chronic stroke patients using functional neuroimaging. Finally, these ideas are discussed and focused on understanding the dynamics involved in the neural circuit underlying audio-motor coupling and how functional connectivity could help to explain the neuroplastic changes observed after therapy in stroke patients.

Original languageEnglish (US)
Pages (from-to)282-293
Number of pages12
JournalAnnals of the New York Academy of Sciences
Issue number1
StatePublished - Apr 2012


  • Auditory-motor coupling
  • Functional connectivity
  • Music-supported therapy
  • Plasticity
  • Stroke

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • History and Philosophy of Science


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