The mechanism and consequences of retrotransposition

Gerald R. Fink, Jef D. Boeke, David J. Garfinkel

    Research output: Contribution to journalArticle

    Abstract

    Ty elements are repeated DNA sequences in yeast that move around the genome through a surprising sequence of events. The element is transcribed into RNA and this RNA is reverse-transcribed into a DNA copy capable of inserting itself into many different chromosomal locations. The presence of reverse transcriptase in cells raises the possibility that reverse transcription has a role in normal cellular processes.

    Original languageEnglish (US)
    Pages (from-to)118-123
    Number of pages6
    JournalTrends in Genetics
    Volume2
    Issue numberC
    DOIs
    StatePublished - 1986

    ASJC Scopus subject areas

    • Genetics

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