The mycobiome-immune axis: The next frontier in pancreatic cancer

Research output: Contribution to journalComment/debatepeer-review

Abstract

In this issue of Cancer Cell, Aftab et al. identify a pro-inflammatory cytokine, IL-33, that is released as a chemoattractant for type 2 immune cells in response to the intratumoral mycobiome. Depletion of fungi or deletion of IL-33 in cancer cells significantly decreases pancreatic ductal adenocarcinoma (PDAC) tumor progression and increases survival.

Original languageEnglish (US)
Pages (from-to)120-122
Number of pages3
JournalCancer Cell
Volume40
Issue number2
DOIs
StatePublished - Feb 14 2022

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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