The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study

Abdulla Shehab; Bayan Al-Dabbagh; Khalid Alhabib; Alawi Alsheikh-Ali; Wael Almahmeed; Kadhim Sulaiman; Ahmed Al-Motarreb; Jassim Al Suwaidi; Ahmad Hersi; Hussam Alfaleh; Nidal Asaad; Shukri Alsaif; Haitham Amin; Muath Alanbaei; Nicolaas Nagelkerke; Abdishakur Abdulle

doi:10.1177/0003319713497087

The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study

Abdulla Shehab, Bayan Al-Dabbagh, Khalid Alhabib, Alawi Alsheikh-Ali, Wael Almahmeed, Kadhim Sulaiman, Ahmed Al-Motarreb, Jassim Al Suwaidi, Ahmad Hersi, Hussam Alfaleh, Nidal Asaad, Shukri Alsaif, Haitham Amin, Muath Alanbaei, Nicolaas Nagelkerke, Abdishakur Abdulle

Public Health Research Center

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Abstract

We investigated the association between in-hospital and peri-hospital mortality and body mass index (BMI)/waist circumference (WC) in a prospective acute coronary syndrome (ACS) registry in the Arabian Gulf. No significant associations with in-hospital mortality were found. Normal BMI had highest peri-hospital mortality, notably those with high WC. In logistic regression of mortality on obesity measures and potential confounders, the effects of obesity measures were no longer significant. In-hospital death increased by 5% with age and decreased by 42% in males. Mortality increased 3.7-fold with ST-elevation myocardial infarction (STEMI) and 3.0-fold with heart failure (HF) but decreased by 33% with dyslipidemia. Peri-hospital death increased by 4% with age and decreased by 30% in males. Mortality increased 2.8-fold with STEMI and 2.4-fold with HF. In- and peri-hospital mortality in ACS is significantly associated with age, gender, STEMI, HF, and dyslipidemia but not obesity measures.

Original language	English (US)
Pages (from-to)	585-589
Number of pages	5
Journal	Angiology
Volume	65
Issue number	7
DOIs	https://doi.org/10.1177/0003319713497087
State	Published - Aug 2014

Keywords

ACS
Arabian Gulf
mortality
obesity

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1177/0003319713497087

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Shehab, A., Al-Dabbagh, B., Alhabib, K., Alsheikh-Ali, A., Almahmeed, W., Sulaiman, K., Al-Motarreb, A., Suwaidi, J. A., Hersi, A., Alfaleh, H., Asaad, N., Alsaif, S., Amin, H., Alanbaei, M., Nagelkerke, N., & Abdulle, A. (2014). The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study. Angiology, 65(7), 585-589. https://doi.org/10.1177/0003319713497087

Shehab, A, Al-Dabbagh, B, Alhabib, K, Alsheikh-Ali, A, Almahmeed, W, Sulaiman, K, Al-Motarreb, A, Suwaidi, JA, Hersi, A, Alfaleh, H, Asaad, N, Alsaif, S, Amin, H, Alanbaei, M, Nagelkerke, N & Abdulle, A 2014, 'The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study', Angiology, vol. 65, no. 7, pp. 585-589. https://doi.org/10.1177/0003319713497087

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abstract = "We investigated the association between in-hospital and peri-hospital mortality and body mass index (BMI)/waist circumference (WC) in a prospective acute coronary syndrome (ACS) registry in the Arabian Gulf. No significant associations with in-hospital mortality were found. Normal BMI had highest peri-hospital mortality, notably those with high WC. In logistic regression of mortality on obesity measures and potential confounders, the effects of obesity measures were no longer significant. In-hospital death increased by 5% with age and decreased by 42% in males. Mortality increased 3.7-fold with ST-elevation myocardial infarction (STEMI) and 3.0-fold with heart failure (HF) but decreased by 33% with dyslipidemia. Peri-hospital death increased by 4% with age and decreased by 30% in males. Mortality increased 2.8-fold with STEMI and 2.4-fold with HF. In- and peri-hospital mortality in ACS is significantly associated with age, gender, STEMI, HF, and dyslipidemia but not obesity measures.",

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doi = "10.1177/0003319713497087",

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AU - Shehab, Abdulla

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AU - Alsheikh-Ali, Alawi

AU - Almahmeed, Wael

AU - Sulaiman, Kadhim

AU - Al-Motarreb, Ahmed

AU - Suwaidi, Jassim Al

AU - Hersi, Ahmad

AU - Alfaleh, Hussam

AU - Asaad, Nidal

AU - Alsaif, Shukri

AU - Amin, Haitham

AU - Alanbaei, Muath

AU - Nagelkerke, Nicolaas

AU - Abdulle, Abdishakur

PY - 2014/8

Y1 - 2014/8

N2 - We investigated the association between in-hospital and peri-hospital mortality and body mass index (BMI)/waist circumference (WC) in a prospective acute coronary syndrome (ACS) registry in the Arabian Gulf. No significant associations with in-hospital mortality were found. Normal BMI had highest peri-hospital mortality, notably those with high WC. In logistic regression of mortality on obesity measures and potential confounders, the effects of obesity measures were no longer significant. In-hospital death increased by 5% with age and decreased by 42% in males. Mortality increased 3.7-fold with ST-elevation myocardial infarction (STEMI) and 3.0-fold with heart failure (HF) but decreased by 33% with dyslipidemia. Peri-hospital death increased by 4% with age and decreased by 30% in males. Mortality increased 2.8-fold with STEMI and 2.4-fold with HF. In- and peri-hospital mortality in ACS is significantly associated with age, gender, STEMI, HF, and dyslipidemia but not obesity measures.

AB - We investigated the association between in-hospital and peri-hospital mortality and body mass index (BMI)/waist circumference (WC) in a prospective acute coronary syndrome (ACS) registry in the Arabian Gulf. No significant associations with in-hospital mortality were found. Normal BMI had highest peri-hospital mortality, notably those with high WC. In logistic regression of mortality on obesity measures and potential confounders, the effects of obesity measures were no longer significant. In-hospital death increased by 5% with age and decreased by 42% in males. Mortality increased 3.7-fold with ST-elevation myocardial infarction (STEMI) and 3.0-fold with heart failure (HF) but decreased by 33% with dyslipidemia. Peri-hospital death increased by 4% with age and decreased by 30% in males. Mortality increased 2.8-fold with STEMI and 2.4-fold with HF. In- and peri-hospital mortality in ACS is significantly associated with age, gender, STEMI, HF, and dyslipidemia but not obesity measures.

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The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study

Abstract

Keywords

ASJC Scopus subject areas

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