The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study

Abdulla Shehab, Bayan Al-Dabbagh, Khalid Alhabib, Alawi Alsheikh-Ali, Wael Almahmeed, Kadhim Sulaiman, Ahmed Al-Motarreb, Jassim Al Suwaidi, Ahmad Hersi, Hussam Alfaleh, Nidal Asaad, Shukri Alsaif, Haitham Amin, Muath Alanbaei, Nicolaas Nagelkerke, Abdishakur Abdulle

Research output: Contribution to journalArticle

Abstract

We investigated the association between in-hospital and peri-hospital mortality and body mass index (BMI)/waist circumference (WC) in a prospective acute coronary syndrome (ACS) registry in the Arabian Gulf. No significant associations with in-hospital mortality were found. Normal BMI had highest peri-hospital mortality, notably those with high WC. In logistic regression of mortality on obesity measures and potential confounders, the effects of obesity measures were no longer significant. In-hospital death increased by 5% with age and decreased by 42% in males. Mortality increased 3.7-fold with ST-elevation myocardial infarction (STEMI) and 3.0-fold with heart failure (HF) but decreased by 33% with dyslipidemia. Peri-hospital death increased by 4% with age and decreased by 30% in males. Mortality increased 2.8-fold with STEMI and 2.4-fold with HF. In- and peri-hospital mortality in ACS is significantly associated with age, gender, STEMI, HF, and dyslipidemia but not obesity measures.

Original languageEnglish (US)
Pages (from-to)585-589
Number of pages5
JournalAngiology
Volume65
Issue number7
DOIs
StatePublished - Aug 2014

Keywords

  • ACS
  • Arabian Gulf
  • mortality
  • obesity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Shehab, A., Al-Dabbagh, B., Alhabib, K., Alsheikh-Ali, A., Almahmeed, W., Sulaiman, K., Al-Motarreb, A., Suwaidi, J. A., Hersi, A., Alfaleh, H., Asaad, N., Alsaif, S., Amin, H., Alanbaei, M., Nagelkerke, N., & Abdulle, A. (2014). The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study. Angiology, 65(7), 585-589. https://doi.org/10.1177/0003319713497087