TY - JOUR
T1 - The perirhinal cortex
AU - Suzuki, Wendy A.
AU - Naya, Yuji
PY - 2014/7
Y1 - 2014/7
N2 - Anatomically, the perirhinal cortex sits at the boundary between the medial temporal lobe and the ventral visual pathway. It has prominent interconnections not only with both these systems, but also with a wide range of unimodal and polymodal association areas. Consistent with these diverse projections, neurophysiological studies reveal a multidimensional set of mnemonic signals that include stimulus familiarity, within- and between-domain associations, associative recall, and delay-based persistence. This wide range of perirhinal memory signals not only includes signals that are largely unique to the perirhinal cortex (i.e., object familiarity), consistent with dual-process theories, but also includes a range of signals (i.e., associative flexibility and recall) that are strongly associated with the hippocampus, consistent with single-process theories. These neurophysiological findings have important implications for bridging the gap between single-process and dual-process models of medial temporal lobe function. ©
AB - Anatomically, the perirhinal cortex sits at the boundary between the medial temporal lobe and the ventral visual pathway. It has prominent interconnections not only with both these systems, but also with a wide range of unimodal and polymodal association areas. Consistent with these diverse projections, neurophysiological studies reveal a multidimensional set of mnemonic signals that include stimulus familiarity, within- and between-domain associations, associative recall, and delay-based persistence. This wide range of perirhinal memory signals not only includes signals that are largely unique to the perirhinal cortex (i.e., object familiarity), consistent with dual-process theories, but also includes a range of signals (i.e., associative flexibility and recall) that are strongly associated with the hippocampus, consistent with single-process theories. These neurophysiological findings have important implications for bridging the gap between single-process and dual-process models of medial temporal lobe function. ©
KW - Association memory
KW - Declarative memory
KW - Medial temporal lobe
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U2 - 10.1146/annurev-neuro-071013-014207
DO - 10.1146/annurev-neuro-071013-014207
M3 - Review article
C2 - 25032492
AN - SCOPUS:84904615444
SN - 0147-006X
VL - 37
SP - 39
EP - 53
JO - Annual Review of Neuroscience
JF - Annual Review of Neuroscience
ER -