The role of neuropeptides in regulating airway function. Postsecretory metabolism of peptides.

N. W. Bunnett

Research output: Contribution to journalReview article

Abstract

Peptide hormones and neurotransmitters play an essential role in regulation of cellular metabolism. Once released from an endocrine cell or nerve ending, peptides encounter membrane-bound and soluble peptidases. The peptidases inactivate peptides or form fragments with novel biologic activity. Therefore, peptidases must play a major role in homeostatic control, but this aspect of regulation has been a neglected area. This review examines the postsecretory metabolism of biologically active peptides in the brain and alimentary tract, 2 organs in which peptide regulation is of crucial importance.

Original languageEnglish (US)
Pages (from-to)S27-34
JournalAmerican Review of Respiratory Disease
Volume136
Issue number6 Pt 2
StatePublished - Dec 1987

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Fingerprint Dive into the research topics of 'The role of neuropeptides in regulating airway function. Postsecretory metabolism of peptides.'. Together they form a unique fingerprint.

  • Cite this