The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Elena Flowers; Alka M. Kanaya; Li Zhang; Bradley E. Aouizerat

doi:10.3389/fgene.2022.853633

The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Elena Flowers, Alka M. Kanaya, Li Zhang, Bradley E. Aouizerat

Oral and Maxillofacial Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.

Original language	English (US)
Article number	853633
Journal	Frontiers in Genetics
Volume	13
DOIs	https://doi.org/10.3389/fgene.2022.853633
State	Published - Mar 18 2022

Keywords

ancestry
biomarker
diabetes
diabetes prevention program
fasting blood glucose
microRNA
prediabetes
race/ethnicity

ASJC Scopus subject areas

Molecular Medicine
Genetics
Genetics(clinical)

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10.3389/fgene.2022.853633

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abstract = "Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.",

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author = "Elena Flowers and Kanaya, {Alka M.} and Li Zhang and Aouizerat, {Bradley E.}",

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KW - microRNA

KW - prediabetes

KW - race/ethnicity

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The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Abstract

Keywords

ASJC Scopus subject areas

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