The tactile sensors of the gut

Sarah A. Najjar, Kara Gross Margolis

Research output: Contribution to journalShort surveypeer-review

Abstract

In a recent study, Treichel, Finholm et al. showed that the mechanoreceptor Piezo2 enables enteroendocrine cells in the intestinal epithelium to sense luminal contents. Through neuroepithelial signaling, these cells modulate intestinal motility and transit of digestive products.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalTrends in Neurosciences
Volume45
Issue number3
DOIs
StatePublished - Mar 2022

Keywords

  • GI physiology
  • Piezo2
  • enteroendocrine cells
  • ion channels
  • mechanosensitivity
  • neuroepithelial connection

ASJC Scopus subject areas

  • General Neuroscience

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