TY - JOUR
T1 - The weekly calendar planning activity in multiple sclerosis
T2 - A top-down assessment of executive functions
AU - Goverover, Yael
AU - Toglia, Joan
AU - DeLuca, John
N1 - Funding Information:
This study was funded by an Investigator Initiated Grant/Trial Award from Biogen [US-MG-13-10511].
Publisher Copyright:
© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2020/8/8
Y1 - 2020/8/8
N2 - Deficits in executive functioning are detrimental to employment, daily functioning and quality of life, however their precise nature in multiple sclerosis (MS) remains underspecified. The aims of this study were to: (1) describe the executive processes affected in MS, using a top-down (Weekly Calendar Planning Activity; WCPA) and bottom-up (Delis-Kaplan Executive Function System; DKEFS) assessment tools; (2) explore relationships between performance on the WCPA and DKEFS with a test of everyday functional performance, Actual RealityTM (AR). Methods: Sixty two participants with MS with and without cognitive impairments (n = 21 and 41, respectively) and 38 Healthy Controls (HC) completed the WCPA, two selected subtests of the DKEFS, and AR. Results: The MS group with cognitive impairments performed worse compared with the MS with no cognitive impairments and HC on both the WCPA and DKEFS. Better scores on the DKEFS were associated with better performance of the WCPA. WCPA was a significant predictor of three of the four AR variables. The DKEFS was a significant predictor of time to perform the AR. The results support the use of the WCPA as an assessment of executive functions in persons with MS. It embodies processes such as environmental monitoring, planning and problem solving, and self-regulation.
AB - Deficits in executive functioning are detrimental to employment, daily functioning and quality of life, however their precise nature in multiple sclerosis (MS) remains underspecified. The aims of this study were to: (1) describe the executive processes affected in MS, using a top-down (Weekly Calendar Planning Activity; WCPA) and bottom-up (Delis-Kaplan Executive Function System; DKEFS) assessment tools; (2) explore relationships between performance on the WCPA and DKEFS with a test of everyday functional performance, Actual RealityTM (AR). Methods: Sixty two participants with MS with and without cognitive impairments (n = 21 and 41, respectively) and 38 Healthy Controls (HC) completed the WCPA, two selected subtests of the DKEFS, and AR. Results: The MS group with cognitive impairments performed worse compared with the MS with no cognitive impairments and HC on both the WCPA and DKEFS. Better scores on the DKEFS were associated with better performance of the WCPA. WCPA was a significant predictor of three of the four AR variables. The DKEFS was a significant predictor of time to perform the AR. The results support the use of the WCPA as an assessment of executive functions in persons with MS. It embodies processes such as environmental monitoring, planning and problem solving, and self-regulation.
KW - Activities of daily living
KW - assessment
KW - executive functions
KW - multiple sclerosis
UR - http://www.scopus.com/inward/record.url?scp=85062373010&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85062373010&partnerID=8YFLogxK
U2 - 10.1080/09602011.2019.1584573
DO - 10.1080/09602011.2019.1584573
M3 - Article
C2 - 30810484
AN - SCOPUS:85062373010
SN - 0960-2011
VL - 30
SP - 1372
EP - 1387
JO - Neuropsychological Rehabilitation
JF - Neuropsychological Rehabilitation
IS - 7
ER -