Theoretical investigation of the rubicordifolin cascade

Jean Philip Lumb, Jamin L. Krinsky, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

The results of a theoretical investigation on the complex cascade reaction leading to the natural product rubicordifolin are reported. These computations analyze the discrete transformations that are required during the conversion of the vinyl naphthoquinone starting material into the natural product, including two pseudopericyclic cyclizations as well as a diastereoselective, hetero-Diels-Alder reaction.

Original languageEnglish (US)
Pages (from-to)5162-5165
Number of pages4
JournalOrganic Letters
Volume12
Issue number22
DOIs
StatePublished - Nov 19 2010

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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  • Cite this

    Lumb, J. P., Krinsky, J. L., & Trauner, D. (2010). Theoretical investigation of the rubicordifolin cascade. Organic Letters, 12(22), 5162-5165. https://doi.org/10.1021/ol102157d