K teorii kompaktizatsii DNK v polimernom rastvore.

A. I. Grosberg; I. I. Erukhimovich; E. I. Shakhnovich

K teorii kompaktizatsii DNK v polimernom rastvore.

Translated title of the contribution: Theory of DNA compactization in a polymer solution

A. I. Grosberg, I. I. Erukhimovich, E. I. Shakhnovich

Research output: Contribution to journal › Article › peer-review

Abstract

A theory of DNA compactization is suggested. It is based on the concept about compact DNA globule as a polymeric one. The polymeric solution is considered as a strongly fluctuating system, and the double helical DNA as a rigid unifilar homopolymer. The globule is shown to appear in a diluted polymeric solution. The character of relative phase transition is analysed. With an increase of polymeric solution concentration the size of the DNA globule should decrease and the optic activity increase. Conditions are indicated under which the decompactization of DNA takes place at high concentrations of polymeric solution. This event is accompanied by an abrupt increase of DNA size and a decrease of optical activity.

Translated title of the contribution	Theory of DNA compactization in a polymer solution
Original language	Russian
Pages (from-to)	897-905
Number of pages	9
Journal	Biofizika
Volume	26
Issue number	5
State	Published - Sep 1981

ASJC Scopus subject areas

General Medicine

Cite this

@article{a936eda9dfb34adf869509140e1fd952,

title = "K teorii kompaktizatsii DNK v polimernom rastvore.",

abstract = "A theory of DNA compactization is suggested. It is based on the concept about compact DNA globule as a polymeric one. The polymeric solution is considered as a strongly fluctuating system, and the double helical DNA as a rigid unifilar homopolymer. The globule is shown to appear in a diluted polymeric solution. The character of relative phase transition is analysed. With an increase of polymeric solution concentration the size of the DNA globule should decrease and the optic activity increase. Conditions are indicated under which the decompactization of DNA takes place at high concentrations of polymeric solution. This event is accompanied by an abrupt increase of DNA size and a decrease of optical activity.",

author = "Grosberg, {A. I.} and Erukhimovich, {I. I.} and Shakhnovich, {E. I.}",

year = "1981",

month = sep,

language = "Russian",

volume = "26",

pages = "897--905",

journal = "Biofizika",

issn = "0006-3029",

publisher = "Izdatel'stvo Nauka",

number = "5",

}

TY - JOUR

T1 - K teorii kompaktizatsii DNK v polimernom rastvore.

AU - Grosberg, A. I.

AU - Erukhimovich, I. I.

AU - Shakhnovich, E. I.

PY - 1981/9

Y1 - 1981/9

N2 - A theory of DNA compactization is suggested. It is based on the concept about compact DNA globule as a polymeric one. The polymeric solution is considered as a strongly fluctuating system, and the double helical DNA as a rigid unifilar homopolymer. The globule is shown to appear in a diluted polymeric solution. The character of relative phase transition is analysed. With an increase of polymeric solution concentration the size of the DNA globule should decrease and the optic activity increase. Conditions are indicated under which the decompactization of DNA takes place at high concentrations of polymeric solution. This event is accompanied by an abrupt increase of DNA size and a decrease of optical activity.

AB - A theory of DNA compactization is suggested. It is based on the concept about compact DNA globule as a polymeric one. The polymeric solution is considered as a strongly fluctuating system, and the double helical DNA as a rigid unifilar homopolymer. The globule is shown to appear in a diluted polymeric solution. The character of relative phase transition is analysed. With an increase of polymeric solution concentration the size of the DNA globule should decrease and the optic activity increase. Conditions are indicated under which the decompactization of DNA takes place at high concentrations of polymeric solution. This event is accompanied by an abrupt increase of DNA size and a decrease of optical activity.

UR - http://www.scopus.com/inward/record.url?scp=0019620529&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019620529&partnerID=8YFLogxK

M3 - Article

C2 - 7317480

AN - SCOPUS:0019620529

SN - 0006-3029

VL - 26

SP - 897

EP - 905

JO - Biofizika

JF - Biofizika

IS - 5

ER -

K teorii kompaktizatsii DNK v polimernom rastvore.

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this