K teorii kompaktizatsii DNK v polimernom rastvore.

Translated title of the contribution: Theory of DNA compactization in a polymer solution

A. I. Grosberg, I. I. Erukhimovich, E. I. Shakhnovich

    Research output: Contribution to journalArticle

    Abstract

    A theory of DNA compactization is suggested. It is based on the concept about compact DNA globule as a polymeric one. The polymeric solution is considered as a strongly fluctuating system, and the double helical DNA as a rigid unifilar homopolymer. The globule is shown to appear in a diluted polymeric solution. The character of relative phase transition is analysed. With an increase of polymeric solution concentration the size of the DNA globule should decrease and the optic activity increase. Conditions are indicated under which the decompactization of DNA takes place at high concentrations of polymeric solution. This event is accompanied by an abrupt increase of DNA size and a decrease of optical activity.

    Translated title of the contributionTheory of DNA compactization in a polymer solution
    Original languageRussian
    Pages (from-to)897-905
    Number of pages9
    JournalBiofizika
    Volume26
    Issue number5
    StatePublished - Sep 1981

    ASJC Scopus subject areas

    • Medicine(all)

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  • Cite this

    Grosberg, A. I., Erukhimovich, I. I., & Shakhnovich, E. I. (1981). K teorii kompaktizatsii DNK v polimernom rastvore. Biofizika, 26(5), 897-905.