K teorii toroidal'noǐ kompaktnoǐ formy DNK v polimernom rastvore.

Translated title of the contribution: Theory of the toroidal compact form of DNA in a polymer solution

A. I. Grosberg, A. V. Zhestkov

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A diagram of the states of single long rigid DNA macromolecule in solution of short flexible polymer was plotted. It has been shown that the compacting effect of the polymer solvent on DNA can be interpreted as hydrostatic pressure of coils gas on impermeable "walls" of the DNA globule. Conditions were found for the existence of compact (globular) states in the form of a sphere (stable for a very long DNA) and tore (for a relatively short one). Possibility of intramolecular liquidcrystalline orderliness of DNA segments in a globule was analyzed. Regions of realization of both regimes were studied: when compression with an added polymer was equalized by the forces of steric repulsion of DNA segments and when it was balanced by the elasticity of the DNA chain bendings.

    Translated title of the contributionTheory of the toroidal compact form of DNA in a polymer solution
    Original languageRussian
    Pages (from-to)233-238
    Number of pages6
    JournalBiofizika
    Volume30
    Issue number2
    StatePublished - Mar 1985

    ASJC Scopus subject areas

    • Medicine(all)

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