TY - JOUR
T1 - Therapeutic synthetic and natural materials for immunoengineering
AU - Slezak, Anna
AU - Chang, Kevin
AU - Hossainy, Samir
AU - Mansurov, Aslan
AU - Rowan, Stuart J.
AU - Hubbell, Jeffrey A.
AU - Guler, Mustafa O.
N1 - Publisher Copyright:
© 2024 The Royal Society of Chemistry.
PY - 2024/1/3
Y1 - 2024/1/3
N2 - Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years due to the growing demand for effective therapies that can target and regulate the immune system. Biologics and biomaterials are emerging as promising tools for controlling immune responses, and a wide variety of materials, including proteins, polymers, nanoparticles, and hydrogels, are being developed for this purpose. In this review article, we explore the different types of materials used in immunoengineering applications, their properties and design principles, and highlight the latest therapeutic materials advancements. Recent works in adjuvants, vaccines, immune tolerance, immunotherapy, and tissue models for immunoengineering studies are discussed.
AB - Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years due to the growing demand for effective therapies that can target and regulate the immune system. Biologics and biomaterials are emerging as promising tools for controlling immune responses, and a wide variety of materials, including proteins, polymers, nanoparticles, and hydrogels, are being developed for this purpose. In this review article, we explore the different types of materials used in immunoengineering applications, their properties and design principles, and highlight the latest therapeutic materials advancements. Recent works in adjuvants, vaccines, immune tolerance, immunotherapy, and tissue models for immunoengineering studies are discussed.
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U2 - 10.1039/d3cs00805c
DO - 10.1039/d3cs00805c
M3 - Review article
C2 - 38170619
AN - SCOPUS:85181821516
SN - 0306-0012
VL - 53
SP - 1789
EP - 1822
JO - Chemical Society Reviews
JF - Chemical Society Reviews
IS - 4
ER -