Three-dimensional optical tomographic brain imaging in small animals

A. Y. Bluestone, G. S. Abdoulaev, J. M. Lasker, M. Stewart, A. H. Hielscher

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have developed a brain imaging system that uses continuous back-reflected light intensities to obtain spatially resolved, volumetric maps of oxy- and deoxy-hemoglobin in small animals. We report on numerical results as well as experimental studies performed on rats. The numerical study verified the ability to spatially localize changes in the optical properties. The preliminary experimental results focused on visualizing the three-dimensional hemodynamic changes in a rat brain in response to perturbations in the inspired CO2 concentration.

Original languageEnglish (US)
Title of host publicationBiomedical Topical Meeting, BIOMED 2002
PublisherOptica Publishing Group (formerly OSA)
Pages44-46
Number of pages3
ISBN (Electronic)1557527024
StatePublished - 2002
EventBiomedical Topical Meeting, BIOMED 2002 - Miami Beach, United States
Duration: Apr 7 2002Apr 10 2002

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceBiomedical Topical Meeting, BIOMED 2002
Country/TerritoryUnited States
CityMiami Beach
Period4/7/024/10/02

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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