Abstract
We report on the first three dimensional tomographic localization of vascular reactivity in the brain. Using a model-based iterative image reconstruction algorithm we show the spatial distribution of changes in the absorption coefficient caused by changes in blood volume. Unlike currently available topographic reconstruction techniques, three-dimensional, volumetric reconstruction schemes promise to be capable of spatially distinguishing between signals originating in the cerebral cortex from those originating in the overlying tissues.
Original language | English (US) |
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Pages (from-to) | 258-268 |
Number of pages | 11 |
Journal | Proceedings of SPIE - The International Society for Optical Engineering |
Volume | 4250 |
DOIs | |
State | Published - 2001 |
Event | Optical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States Duration: Jan 21 2001 → Jan 23 2001 |
Keywords
- Brain imaging
- Diffuse optical tomography
- Reverse-problem
- Three-dimensional imaging
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering