Three-dimensional retinal imaging with ultrahigh resolution, Fourier/spectral domain optical coherence tomography

Vivek Srinivasan; Maciej Wojtkowski; Tony Ko; Mariana Carvalho; James Fujimoto; Jay Duker; Joel Schumann; Andrzej Kowalczyk

doi:10.1117/12.591367

Three-dimensional retinal imaging with ultrahigh resolution, Fourier/spectral domain optical coherence tomography

Vivek Srinivasan, Maciej Wojtkowski, Tony Ko, Mariana Carvalho, James Fujimoto, Jay Duker, Joel Schumann, Andrzej Kowalczyk

Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

Ultrahigh resolution OCT using broadband light sources achieves improved axial image resolutions of ∼ 2-3 urn compared to standard 10 um resolution OCT used in current commercial instruments. High-speed OCT using Fourier/spectral domain detection enables dramatic increases in imaging speeds. 3D OCT retinal imaging is performed in human subjects using high-speed, ultrahigh resolution OCT, and the concept of an OCT fundus image is introduced. Three-dimensional data and high quality cross-sectional images of retinal pathologies are presented. These results show that 3D OCT may be used to improve coverage of the retina, precision of cross-sectional image registration, quality of cross-sectional images, and visualization of subtle changes in retinal topography. 3D OCT imaging and mapping promise to help elucidate the structural changes associated with retinal disease as well as to improve early diagnosis and monitoring of disease progression and response to treatment.

Original language	English (US)
Article number	19
Pages (from-to)	90-99
Number of pages	10
Journal	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	5688
DOIs	https://doi.org/10.1117/12.591367
State	Published - 2005
Event	Ophtalmic Technologies XV - San Jose, CA, United States Duration: Jan 22 2005 → Jan 25 2005

Keywords

3D
Mapping
Ophthalmology
Optical Coherence Tomography
Rendering
Segmentation
StratusOCT

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

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10.1117/12.591367

Cite this

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title = "Three-dimensional retinal imaging with ultrahigh resolution, Fourier/spectral domain optical coherence tomography",

abstract = "Ultrahigh resolution OCT using broadband light sources achieves improved axial image resolutions of ∼ 2-3 urn compared to standard 10 um resolution OCT used in current commercial instruments. High-speed OCT using Fourier/spectral domain detection enables dramatic increases in imaging speeds. 3D OCT retinal imaging is performed in human subjects using high-speed, ultrahigh resolution OCT, and the concept of an OCT fundus image is introduced. Three-dimensional data and high quality cross-sectional images of retinal pathologies are presented. These results show that 3D OCT may be used to improve coverage of the retina, precision of cross-sectional image registration, quality of cross-sectional images, and visualization of subtle changes in retinal topography. 3D OCT imaging and mapping promise to help elucidate the structural changes associated with retinal disease as well as to improve early diagnosis and monitoring of disease progression and response to treatment.",

keywords = "3D, Mapping, Ophthalmology, Optical Coherence Tomography, Rendering, Segmentation, StratusOCT",

author = "Vivek Srinivasan and Maciej Wojtkowski and Tony Ko and Mariana Carvalho and James Fujimoto and Jay Duker and Joel Schumann and Andrzej Kowalczyk",

year = "2005",

doi = "10.1117/12.591367",

language = "English (US)",

volume = "5688",

pages = "90--99",

journal = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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AU - Srinivasan, Vivek

AU - Wojtkowski, Maciej

AU - Ko, Tony

AU - Carvalho, Mariana

AU - Fujimoto, James

AU - Duker, Jay

AU - Schumann, Joel

AU - Kowalczyk, Andrzej

PY - 2005

Y1 - 2005

N2 - Ultrahigh resolution OCT using broadband light sources achieves improved axial image resolutions of ∼ 2-3 urn compared to standard 10 um resolution OCT used in current commercial instruments. High-speed OCT using Fourier/spectral domain detection enables dramatic increases in imaging speeds. 3D OCT retinal imaging is performed in human subjects using high-speed, ultrahigh resolution OCT, and the concept of an OCT fundus image is introduced. Three-dimensional data and high quality cross-sectional images of retinal pathologies are presented. These results show that 3D OCT may be used to improve coverage of the retina, precision of cross-sectional image registration, quality of cross-sectional images, and visualization of subtle changes in retinal topography. 3D OCT imaging and mapping promise to help elucidate the structural changes associated with retinal disease as well as to improve early diagnosis and monitoring of disease progression and response to treatment.

AB - Ultrahigh resolution OCT using broadband light sources achieves improved axial image resolutions of ∼ 2-3 urn compared to standard 10 um resolution OCT used in current commercial instruments. High-speed OCT using Fourier/spectral domain detection enables dramatic increases in imaging speeds. 3D OCT retinal imaging is performed in human subjects using high-speed, ultrahigh resolution OCT, and the concept of an OCT fundus image is introduced. Three-dimensional data and high quality cross-sectional images of retinal pathologies are presented. These results show that 3D OCT may be used to improve coverage of the retina, precision of cross-sectional image registration, quality of cross-sectional images, and visualization of subtle changes in retinal topography. 3D OCT imaging and mapping promise to help elucidate the structural changes associated with retinal disease as well as to improve early diagnosis and monitoring of disease progression and response to treatment.

KW - 3D

KW - Mapping

KW - Ophthalmology

KW - Optical Coherence Tomography

KW - Rendering

KW - Segmentation

KW - StratusOCT

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ER -

Three-dimensional retinal imaging with ultrahigh resolution, Fourier/spectral domain optical coherence tomography

Abstract

Keywords

ASJC Scopus subject areas

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