Three dimensional visualization of proteins in cellular interactions

Colin R F Monks; Patricia J. Crossno; George Davidson; Constantine Pavlakos; Abraham Kupfer; Claudio Silva; Brian Wylie

Three dimensional visualization of proteins in cellular interactions

Colin R F Monks, Patricia J. Crossno, George Davidson, Constantine Pavlakos, Abraham Kupfer, Claudio Silva, Brian Wylie

Urban Initiative

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

Original language	English (US)
Title of host publication	Proceedings of the IEEE Visualization Conference
Editors	Anon
Publisher	IEEE
Pages	363-366
Number of pages	4
State	Published - 1996
Event	Proceedings of the 1996 IEEE Visualization Conference - San Francisco, CA, USA Duration: Oct 27 1996 → Nov 1 1996

Other

Other	Proceedings of the 1996 IEEE Visualization Conference
City	San Francisco, CA, USA
Period	10/27/96 → 11/1/96

ASJC Scopus subject areas

General Computer Science
General Engineering

Cite this

@inproceedings{e72d470b12074c8b91b266c215ff5e72,

title = "Three dimensional visualization of proteins in cellular interactions",

abstract = "In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.",

author = "Monks, {Colin R F} and Crossno, {Patricia J.} and George Davidson and Constantine Pavlakos and Abraham Kupfer and Claudio Silva and Brian Wylie",

year = "1996",

language = "English (US)",

pages = "363--366",

editor = "Anon",

booktitle = "Proceedings of the IEEE Visualization Conference",

publisher = "IEEE",

note = "Proceedings of the 1996 IEEE Visualization Conference ; Conference date: 27-10-1996 Through 01-11-1996",

}

TY - GEN

T1 - Three dimensional visualization of proteins in cellular interactions

AU - Monks, Colin R F

AU - Crossno, Patricia J.

AU - Davidson, George

AU - Pavlakos, Constantine

AU - Kupfer, Abraham

AU - Silva, Claudio

AU - Wylie, Brian

PY - 1996

Y1 - 1996

N2 - In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

AB - In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

UR - http://www.scopus.com/inward/record.url?scp=0030411074&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030411074&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0030411074

SP - 363

EP - 366

BT - Proceedings of the IEEE Visualization Conference

A2 - Anon, null

PB - IEEE

T2 - Proceedings of the 1996 IEEE Visualization Conference

Y2 - 27 October 1996 through 1 November 1996

ER -

Three dimensional visualization of proteins in cellular interactions

Abstract

Other

ASJC Scopus subject areas

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