Three dimensional visualization of proteins in cellular interactions

Colin R F Monks, Patricia J. Crossno, George Davidson, Constantine Pavlakos, Abraham Kupfer, Claudio Silva, Brian Wylie

Research output: Chapter in Book/Report/Conference proceedingConference contribution


In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Visualization Conference
Editors Anon
Number of pages4
StatePublished - 1996
EventProceedings of the 1996 IEEE Visualization Conference - San Francisco, CA, USA
Duration: Oct 27 1996Nov 1 1996


OtherProceedings of the 1996 IEEE Visualization Conference
CitySan Francisco, CA, USA

ASJC Scopus subject areas

  • General Computer Science
  • General Engineering


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