Time-resolved photon migration in a heterogeneous tissue-vessel model

Hanli Liu, Andreas H. Hielscher, Dean C. Kurth, Steven L. Jacques, Britton Chance

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We investigate the relationship between the apparent absorption coefficient and actual absorption coefficient inside the vessels. This analytical formula predicts that the apparent absorption coefficient measured on a biological organ is a volume-weighted sum of the absorption coefficients of different absorbing components. Further, we present some apparent absorption coefficients measured in vivo in animals and humans and show that ignoring the background absorption can lead to significant errors in oxygenation determination.

    Original languageEnglish (US)
    Title of host publicationOptical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media
    Subtitle of host publicationTheory, Human Studies, and Instrumentation
    EditorsBritton Chance, Robert R. Alfano
    PublisherSPIE
    Pages150-156
    Number of pages7
    ISBN (Electronic)9780819417367
    DOIs
    StatePublished - May 30 1995
    EventOptical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation - San Jose, United States
    Duration: Feb 1 1995Feb 28 1995

    Publication series

    NameProceedings of SPIE - The International Society for Optical Engineering
    Volume2389
    ISSN (Print)0277-786X
    ISSN (Electronic)1996-756X

    Other

    OtherOptical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation
    CountryUnited States
    CitySan Jose
    Period2/1/952/28/95

    Keywords

    • blood oxygenation
    • blood vessels
    • hemoglobin absorption
    • Heterogeneity
    • Me-resolved reflectance

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Computer Science Applications
    • Applied Mathematics
    • Electrical and Electronic Engineering

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