Tissue differentiation by diffuse reflectance spectroscopy for automated oral and maxillofacial laser surgery: Ex vivo pilot study

Azhar Zam, Florian Stelzle, Katja Tangermann-Gerk, Werner Adler, Emeka Nkenke, Michael Schmidt, Alexandre Douplik

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Remote laser surgery lacks of haptic feedback during the laser ablation of tissue. Hence, there is a risk of iatrogenic damage or destruction of anatomical structures like nerves or salivary glands. Diffuse reflectance spectroscopy provides a straightforward and simple approach for optical tissue differentiation. We measured diffuse reflectance from seven various tissue types ex vivo. We applied Linear Discriminant Analysis (LDA) to differentiate the seven tissue types and computed the area under the ROC curve (AUC). Special emphasis was taken on the identification of nerves and salivary glands as the most crucial tissue for maxillofacial surgery. The results show a promise for differentiating tissues as guidance for oral and maxillofacial laser surgery by means of diffuse reflectance.

Original languageEnglish (US)
Title of host publicationAdvanced Biomedical and Clinical Diagnostic Systems VIII
DOIs
StatePublished - 2010
EventAdvanced Biomedical and Clinical Diagnostic Systems VIII - San Francisco, CA, United States
Duration: Jan 24 2010Jan 26 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7555
ISSN (Print)1605-7422

Conference

ConferenceAdvanced Biomedical and Clinical Diagnostic Systems VIII
Country/TerritoryUnited States
CitySan Francisco, CA
Period1/24/101/26/10

Keywords

  • Diffuse reflectance
  • Feedback system
  • Laser surgery
  • Linear discriminant analysis
  • Oral and maxillofacial surgery
  • Tissue differentiation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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