Tissue Engineering Strategies for Craniomaxillofacial Surgery: Current Trends in 3D-Printed Bioactive Ceramic Scaffolds

Lukasz Witek, Vasudev Vivekanand Nayak, Christopher M. Runyan, Nick Tovar, Sharbel Elhage, James C. Melville, Simon Young, David H. Kim, Bruce N. Cronstein, Roberto L. Flores, Paulo G. Coelho

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The advancements in craniomaxillofacial surgical reconstruction have led to improvements in patient-specific treatment care. One of the primary goals is to restore form and function by balancing aesthetic, functional and physiological demands while minimizing morbidity to the patient. Although the promise of bone tissue engineering has yet to be fully achieved, clinically, translational developments have been evaluated with favorable results. This chapter reviews the recent and current advances in biomaterials science combined with 3D printing combined with bioactive molecule osteogenic stimulation, and their integration toward the development of devices capable of facilitating craniomaxillofacial bony restoration.

Original languageEnglish (US)
Title of host publicationSpringer Series in Biomaterials Science and Engineering
PublisherSpringer Science and Business Media Deutschland GmbH
Pages55-74
Number of pages20
DOIs
StatePublished - 2022

Publication series

NameSpringer Series in Biomaterials Science and Engineering
Volume18
ISSN (Print)2195-0644
ISSN (Electronic)2195-0652

Keywords

  • 3D Printing
  • Additive Manufacturing
  • Adenosine
  • Bone Tissue Engineering
  • Craniomaxillofacial Surgery
  • Dipyridamole (DIPY)
  • Recombinant Human Bone Morphogenic Protein (rhBMP-2)

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials

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