TY - GEN
T1 - Tomographic Imaging of BiologicalTissue by Time-Resolved, Model-Based, Iterative Image Reconstruction
AU - Hielscher, Andreas H.
AU - Klose, Alexander
AU - Catarious, David
AU - Hanson, Kenneth M.
N1 - Publisher Copyright:
© 1998 Optical Society of America.
PY - 1998
Y1 - 1998
N2 - Currently available tomographic image reconstruction schemes for photon migration tomography (PMT) small are mostly based on the limiting assumptions of perturbations and a priori knowledge of the optical properties of a reference In this work a model based iterative image reconstruction (MOBIIR) method is presented, which does not require the knowledge a reference medium or that the encountered heterogeneities are small perturbations. After a description of the major code structure and a review of the mathematical background, the clinical relevant examples of brain imaging and breast cancer detection are discussed. It is shown that ventricular bleedings in the brain can be detected and that cysts and tumors in the breast can be distinguished using the MOBIIR technique.
AB - Currently available tomographic image reconstruction schemes for photon migration tomography (PMT) small are mostly based on the limiting assumptions of perturbations and a priori knowledge of the optical properties of a reference In this work a model based iterative image reconstruction (MOBIIR) method is presented, which does not require the knowledge a reference medium or that the encountered heterogeneities are small perturbations. After a description of the major code structure and a review of the mathematical background, the clinical relevant examples of brain imaging and breast cancer detection are discussed. It is shown that ventricular bleedings in the brain can be detected and that cysts and tumors in the breast can be distinguished using the MOBIIR technique.
KW - (100.6950) Tomographic image processing
KW - (170.3010) Image reconstruction techniques
KW - (170.3880) Medical and biological imaging
KW - (170.6920) Time-resolved imaging
KW - (290.7050) Turbid media
UR - http://www.scopus.com/inward/record.url?scp=33749751106&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749751106&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33749751106
T3 - Optics InfoBase Conference Papers
SP - 156
EP - 161
BT - Advances in Optical Imaging and Photon Migration, AOIPM 1998
PB - Optica Publishing Group (formerly OSA)
T2 - Advances in Optical Imaging and Photon Migration, AOIPM 1998
Y2 - 8 March 1998
ER -