Tomographic Imaging of BiologicalTissue by Time-Resolved, Model-Based, Iterative Image Reconstruction

Andreas H. Hielscher, Alexander Klose, David Catarious, Kenneth M. Hanson

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Currently available tomographic image reconstruction schemes for photon migration tomography (PMT) small are mostly based on the limiting assumptions of perturbations and a priori knowledge of the optical properties of a reference In this work a model based iterative image reconstruction (MOBIIR) method is presented, which does not require the knowledge a reference medium or that the encountered heterogeneities are small perturbations. After a description of the major code structure and a review of the mathematical background, the clinical relevant examples of brain imaging and breast cancer detection are discussed. It is shown that ventricular bleedings in the brain can be detected and that cysts and tumors in the breast can be distinguished using the MOBIIR technique.

    Original languageEnglish (US)
    Title of host publicationAdvances in Optical Imaging and Photon Migration, AOIPM 1998
    PublisherOptica Publishing Group (formerly OSA)
    Pages156-161
    Number of pages6
    ISBN (Electronic)1557525463
    StatePublished - 1998
    EventAdvances in Optical Imaging and Photon Migration, AOIPM 1998 - Orlando, United States
    Duration: Mar 8 1998 → …

    Publication series

    NameOptics InfoBase Conference Papers

    Conference

    ConferenceAdvances in Optical Imaging and Photon Migration, AOIPM 1998
    Country/TerritoryUnited States
    CityOrlando
    Period3/8/98 → …

    Keywords

    • (100.6950) Tomographic image processing
    • (170.3010) Image reconstruction techniques
    • (170.3880) Medical and biological imaging
    • (170.6920) Time-resolved imaging
    • (290.7050) Turbid media

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Mechanics of Materials

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