Tomographic reconstruction of layered tissue structures

Andreas H. Hielscher, Mohideen Azeez-Jan, Sebastian Bartel

    Research output: Contribution to journalConference articlepeer-review


    In recent years the interest in the determination of optical properties of layered tissue structure has resurfaced. Applications include, for example, studies on layered skin tissue and underlying muscles, imaging of the brain underneath layers of skin, skull, and meninges, and imaging of the fetal head in utero beneath the layered structures of the maternal abdomen. In this work we approach the problem of layered structures in the framework of model-based iterative image reconstruction schemes. These schemes are currently developed to determine the optical properties inside tissue from measurement on the surface. If applied to layered structure these techniques yield substantial improvements over currently available semi-analytical approaches.

    Original languageEnglish (US)
    Pages (from-to)126-133
    Number of pages8
    JournalProceedings of SPIE - The International Society for Optical Engineering
    StatePublished - 2001
    EventPhoton Migration, Optical Coherence Tomography, and Microscopy - Munich, Germany
    Duration: Jun 18 2001Jun 21 2001


    • Image reconstruction techniques
    • Layered structures
    • Tomography
    • Turbid media

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Computer Science Applications
    • Applied Mathematics
    • Electrical and Electronic Engineering


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