O toroidal'nom globuliarnom sostoianii kol'tsevoǐ zamknutoǐ DNK.

Translated title of the contribution: Toroidal globular state of circular DNA

A. I. Grosberg, A. V. Zhestkov

    Research output: Contribution to journalArticle

    Abstract

    The influence of torsional elasticity of the double helix on compactization and structure of circular DNA in a compact form is studied in the case when the compact (globular) particle has a torus shape. For closed circular DNA the topological invariant, linking number of two strains, yields strict connection between conformation of double helix, considered as a unifilar homopolymer, and elastic energy of torsional twisting. The contribution of torsional elasticity to free energy of the toruslike globule is calculated. This contribution is shown to be proportional to the square of superturn's density. Torsional elasticity decreases the equilibrium radius of the toruslike globule formed by circular DNA in comparison with the case of linear DNA. Closure of linear DNA into a ring widens the stability range of the relatively short DNA compact form and tightens it for long DNA.

    Translated title of the contributionToroidal globular state of circular DNA
    Original languageRussian
    Pages (from-to)1153-1156
    Number of pages4
    JournalMolekulyarnaya Biologiya
    Volume19
    Issue number4
    StatePublished - Jul 1985

    ASJC Scopus subject areas

    • Medicine(all)

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  • Cite this

    Grosberg, A. I., & Zhestkov, A. V. (1985). O toroidal'nom globuliarnom sostoianii kol'tsevoǐ zamknutoǐ DNK. Molekulyarnaya Biologiya, 19(4), 1153-1156.