Total synthesis of coralloidolides A, B, C, and E

Thomas J. Kimbrough, Paul A. Roethle, Peter Mayer, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

"Chemical Equation Presented" Mapping the matrix: Several coralloidolides, members of a Mediterranean branch of the furanocembranoid family of diterpenes, have been synthesized. The total syntheses include biomimetic transformations that often occur with high chemoselectivity, thus obviating the need for protecting-group manipulations. The fascinating reactivity of 2,5-diene-1,4dione moieties was explored in detail.

Original languageEnglish (US)
Pages (from-to)2619-2621
Number of pages3
JournalAngewandte Chemie - International Edition
Volume49
Issue number14
DOIs
StatePublished - Mar 29 2010

Keywords

  • Biomimetic synthesis
  • Chemoselectivity
  • Furanocembranoids
  • Lewis acids
  • Total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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  • Cite this

    Kimbrough, T. J., Roethle, P. A., Mayer, P., & Trauner, D. (2010). Total synthesis of coralloidolides A, B, C, and E. Angewandte Chemie - International Edition, 49(14), 2619-2621. https://doi.org/10.1002/anie.200906126