Total synthesis of newbouldine via reductive N-N bond formation

Michael Pangerl, Chambers C. Hughes, Dirk Trauner

Research output: Contribution to journalArticle


The first total synthesis of newbouldine has been achieved employing a new, reductive N-N bond forming reaction. The asymmetric synthesis confirms that the natural product is a racemate.

Original languageEnglish (US)
Pages (from-to)6626-6631
Number of pages6
Issue number33
StatePublished - Aug 14 2010


  • Amathaspiramide F
  • Hydrazone
  • N-N bond
  • Natural product synthesis
  • Newbouldine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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