Total synthesis of (±)-photodeoxytridachione through a Lewis acid catalyzed cyclization

Aubry K. Miller, Dirk Trauner

Research output: Contribution to journalArticlepeer-review


Concerted or stepwise: The concise total synthesis of the molluscan polypropionate photodeoxytridachione (3) features a Lewis acid catalyzed cyclization of tetraenoic ester 1 to form bicylo[3.1.0]hexene 2 as a key step. The stereochemistry of the cyclization can be rationalized in terms of a stepwise or a concerted mechanism.

Original languageEnglish (US)
Pages (from-to)549-552
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number5
StatePublished - Feb 3 2003


  • Cyclization
  • Cycloaddition
  • Homogeneous catalysis
  • Lewis acids
  • Total synthesis

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


Dive into the research topics of 'Total synthesis of (±)-photodeoxytridachione through a Lewis acid catalyzed cyclization'. Together they form a unique fingerprint.

Cite this