Total synthesis of sandresolide B and amphilectolide

Ingrid T. Chen, Irina Baitinger, Lucas Schreyer, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

The total synthesis of the diterpenoids sandresolide B and amphilectolide from a common furan building block is presented. Key steps include palladium-mediated carbonylation, lanthanide catalyzed ring closure, Myers alkylation, intramolecular Friedel-Crafts acylation, photooxygenation, and a Kornblum-DeLaMare rearrangement.

Original languageEnglish (US)
Pages (from-to)166-169
Number of pages4
JournalOrganic Letters
Volume16
Issue number1
DOIs
StatePublished - Jan 3 2014

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Total synthesis of sandresolide B and amphilectolide'. Together they form a unique fingerprint.

  • Cite this

    Chen, I. T., Baitinger, I., Schreyer, L., & Trauner, D. (2014). Total synthesis of sandresolide B and amphilectolide. Organic Letters, 16(1), 166-169. https://doi.org/10.1021/ol403156r